|Other Names||Granulocyte-macrophage colony-stimulating factor, GM-CSF, Colony-stimulating factor, CSF, Molgramostin, Sargramostim, CSF2, GMCSF|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.|
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Provided below are standard protocols that you may find useful for product applications.
CSF2 is a cytokine thatcontrols the production, differentiation, and function ofgranulocytes and macrophages. The active form of the protein isfound extracellularly as a homodimer. This gene has been localizedto a cluster of related genes at chromosome region 5q31, which isknown to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the clusterinclude those encoding interleukins 4, 5, and 13. [provided byRefSeq].
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Beckers, M.M., et al. Eur. J. Intern. Med. 21(4):289-292(2010)Wang, Y., et al. Diabet. Med. 27(4):376-383(2010)Katano, M., et al. Arthritis Res. Ther. 11 (1), R3 (2009) :
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