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BEX1 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9HBH7
Clone Names 90826080
Peptide ID 90826080
Additional Information
Gene ID 55859
Other Names Protein BEX1, Brain-expressed X-linked protein 1, BEX1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BEX1
Function Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity).
Cellular Location Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus.
Tissue Location Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia.
Research Areas
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Background

Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity).

References

Ding, K., et al. Carcinogenesis 30(1):35-42(2009)Foltz, G., et al. Cancer Res. 66(13):6665-6674(2006)Alvarez, E., et al. Gene 357(1):18-28(2005)Quentmeier, H., et al. Leukemia 19(8):1488-1489(2005)Ross, M.T., et al. Nature 434(7031):325-337(2005)

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$ 80.00
Cat# BP10699c
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