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IGSF1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N6C5 |
|---|---|
| Clone Names | 91013159 |
| Gene ID | 3547 |
|---|---|
| Other Names | Immunoglobulin superfamily member 1, IgSF1, Immunoglobulin-like domain-containing protein 1, Inhibin-binding protein, InhBP, Pituitary gland-specific factor 2, p120, IGSF1, IGDC1, KIAA0364, PGSF2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | IGSF1 |
|---|---|
| Synonyms | IGDC1, KIAA0364, PGSF2 |
| Function | Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B (By similarity). Necessary to mediate a specific antagonistic effect of inhibin B on activin- stimulated transcription. |
| Cellular Location | [Isoform 1]: Membrane; Multi-pass membrane protein [Isoform 3]: Secreted. |
| Tissue Location | Highly expressed in pancreas, testis and fetal liver. Moderately expressed in heart, prostate and small intestine Expressed at very low levels in brain, thymus, ovary, colon, fetal lung and fetal kidney. Expressed in muscle. Isoform 3 is expressed in pituitary gland. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the immunoglobulin-likedomain-containing superfamily. Proteins in this superfamily containvarying numbers of immunoglobulin-like domains and are thought toparticipate in the regulation of interactions between cells.Multiple transcript variants encoding different isoforms have beenfound for this gene.
References
Robakis, T., et al. J. Biol. Chem. 283(52):36369-36376(2008)Nakayama, M., et al. Genome Res. 12(11):1773-1784(2002)Tanaka, S., et al. J. Mol. Endocrinol. 28(1):33-44(2002)Gui, Y., et al. J. Clin. Endocrinol. Metab. 86(5):2104-2110(2001)Chapman, S.C., et al. Mol. Endocrinol. 15(4):668-679(2001)
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