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GNMT Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q14749
Other Accession Q5T8W2
Clone Names 4020621
Additional Information
Gene ID 27232
Other Names Glycine N-methyltransferase, GNMT
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1076a was selected from the N-term region of human GNMT. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
Cellular Location Cytoplasm.
Tissue Location Abundant in liver.
Research Areas
Citations (0)

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Glycine N-methyltransferase (GNMT) catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. GNMT acts as an enzyme to regulate the ratio of S-adenosylmethionine to S-adenosylhomocysteine (AdoHcy) and participates in the detoxification pathway in liver cells.


Augoustides-Savvopoulou, P., et al., J. Inherit. Metab. Dis. 26(8):745-759 (2003).Tseng, T.L., et al., Cancer Res. 63(3):647-654 (2003).Luka, Z., et al., Hum. Genet. 110(1):68-74 (2002).Strausberg RL, et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Mudd, S.H., et al., J. Inherit. Metab. Dis. 24(4):448-464 (2001).

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$ 80.00
Cat# BP1076a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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