CE045 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6NTE8 |
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Clone Names | 91119143 |
Gene ID | 51149 |
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Other Names | UPF0544 protein C5orf45, C5orf45 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MRNIP (HGNC:30817) |
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Synonyms | C5orf45 |
Function | Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex (PubMed:27568553). Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair (PubMed:27568553). |
Cellular Location | Nucleus. Nucleus, nucleoplasm. Note=Recruited to sites of DNA damage (PubMed:27568553). Phosphorylation on Ser-115 induces its nuclear localization and promotes genome stability (PubMed:27568553) |
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Provided below are standard protocols that you may find useful for product applications.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
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