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GSDMC Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BYG8 |
|---|---|
| Clone Names | 91119182 |
| Gene ID | 56169 |
|---|---|
| Other Names | Gasdermin-C, Melanoma-derived leucine zipper-containing extranuclear factor, GSDMC, MLZE |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GSDMC {ECO:0000303|PubMed:17350798, ECO:0000312|HGNC:HGNC:7151} |
|---|---|
| Function | [Gasdermin-C]: This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering pyroptosis. |
| Cellular Location | [Gasdermin-C]: Cytoplasm, cytosol |
| Tissue Location | Expressed mainly in trachea and spleen (PubMed:11223543). In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Birnbaum, S., et al. Nat. Genet. 41(4):473-477(2009)Saeki, N., et al. Genes Chromosomes Cancer 48(3):261-271(2009)Tamura, M., et al. Genomics 89(5):618-629(2007)Watabe, K., et al. Jpn. J. Cancer Res. 92(2):140-151(2001)
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