Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
AT8B2 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P98198 |
|---|---|
| Clone Names | 91201013 |
| Gene ID | 57198 |
|---|---|
| Other Names | Phospholipid-transporting ATPase ID, ATPase class I type 8B member 2, P4-ATPase flippase complex alpha subunit ATP8B2, ATP8B2, ATPID, KIAA1137 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ATP8B2 {ECO:0000303|PubMed:12880872} |
|---|---|
| Synonyms | ATPID, KIAA1137 |
| Function | Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane. May contribute to the maintenance of membrane lipid asymmetry. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Efficient exit from the endoplasmic reticulum requires the presence of TMEM30A or TMEM30B |
| Tissue Location | Isoform 3 is ubiquitous, with highest expression in aorta, cerebellum and uterus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the family ofP-type cation transport ATPases, and to the subfamily ofaminophospholipid-transporting ATPases. The aminophospholipidtranslocases transport phosphatidylserine andphosphatidylethanolamine from one side of a bilayer to another.Alternatively spliced transcript variants encoding differentisoforms have been identified.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Harris, M.J., et al. Biochim. Biophys. Acta 1633(2):127-131(2003)Halleck, M.S., et al. Physiol. Genomics 1(3):139-150(1999)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
