|Other Names||Protein Hikeshi, C11orf73|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.|
|Cellular Location||Cytoplasm, cytosol. Nucleus|
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Required for organization and/or function of the secretory apparatus in Clara cells in lung (By similarity).
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
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