|Other Names||GTPase IMAP family member 7, Immunity-associated nucleotide 7 protein, IAN-7, GIMAP7, IAN7|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||The dimer has GTPase activity; the active site contains residues from both subunits.|
|Cellular Location||Lipid droplet. Cytoplasm. Endoplasmic reticulum. Golgi apparatus. Note=Colocalizes with GIMAP2 on the surface of cytoplasmic lipid droplets|
|Tissue Location||Most abundantly expressed in spleen, lymph nodes, and fetal kidney, but also present in the heart and the small intestine. Lower expression levels are found in lung, kidney, liver, and thyroid, salivary, and mammary glands. Also detected in the thymus (PubMed:15474311). Detected in T-cells (PubMed:23454188).|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein belonging to the GTP-bindingsuperfamily and to the immuno-associated nucleotide (IAN) subfamilyof nucleotide-binding proteins. In humans, the IAN subfamily genesare located in a cluster at 7q36.1.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Krucken, J., et al. Gene 341, 291-304 (2004) :Cambot, M., et al. Blood 99(9):3293-3301(2002)Stamm, O., et al. Gene 282 (1-2), 159-167 (2002) :
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