|Other Names||Metaxin-2, Mitochondrial outer membrane import complex protein 2, MTX2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in transport of proteins into the mitochondrion.|
|Cellular Location||Mitochondrion outer membrane. Mitochondrion|
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The protein encoded by this gene is highly similar to themetaxin 2 protein from mouse, which has been shown to interact withthe mitochondrial membrane protein metaxin 1. Because of thissimilarity, it is thought that the encoded protein is peripherallyassociated with the cytosolic face of the outer mitochondrialmembrane, and that it is involved in the import of proteins intothe mitochondrion. Alternative splicing results in multipletranscript variants. A related pseudogene has been identified onchromosome 7.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Xie, J., et al. FEBS Lett. 581(18):3545-3549(2007)Kozjak-Pavlovic, V., et al. EMBO Rep. 8(6):576-582(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Armstrong, L.C., et al. J. Cell. Biochem. 74(1):11-22(1999)
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