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MTX2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O75431 |
|---|---|
| Clone Names | 91201078 |
| Gene ID | 10651 |
|---|---|
| Other Names | Metaxin-2, Mitochondrial outer membrane import complex protein 2, MTX2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MTX2 |
|---|---|
| Function | Involved in transport of proteins into the mitochondrion. |
| Cellular Location | Mitochondrion outer membrane. Mitochondrion |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is highly similar to themetaxin 2 protein from mouse, which has been shown to interact withthe mitochondrial membrane protein metaxin 1. Because of thissimilarity, it is thought that the encoded protein is peripherallyassociated with the cytosolic face of the outer mitochondrialmembrane, and that it is involved in the import of proteins intothe mitochondrion. Alternative splicing results in multipletranscript variants. A related pseudogene has been identified onchromosome 7.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Xie, J., et al. FEBS Lett. 581(18):3545-3549(2007)Kozjak-Pavlovic, V., et al. EMBO Rep. 8(6):576-582(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Armstrong, L.C., et al. J. Cell. Biochem. 74(1):11-22(1999)
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