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CO027 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q2M3C6
Clone Names 91201152
Additional Information
Gene ID 123591
Other Names Transmembrane protein C15orf27, C15orf27
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMEM266 (HGNC:26763)
Function Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum (PubMed:25165868, PubMed:30810529). Despite the presence of a voltage- sensor segment, does not form a functional ion channel and its precise role remains unclear (PubMed:25165868, PubMed:30810529). Undergoes both rapid and slow structural rearrangements in response to changes in voltage (PubMed:30810529). Contains a zinc-binding site that can regulate the slow conformational transition (PubMed:30810529).
Cellular Location Cell membrane; Multi-pass membrane protein. Cell projection, dendrite Perikaryon. Note=Present in the dendrites and soma of cerebellar granule neurons, but not in their axon
Tissue Location Mainly expressed in the cerebellum (PubMed:25165868). Also expressed in cerebral cortex, skeletal muscle and thyroid, but at much lower levels (PubMed:25165868)
Research Areas
Citations (0)
citation

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References

Zody, M.C., et al. Nature 440(7084):671-675(2006)

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$ 277.78
Cat# BP10811b
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