|Other Names||Ankyrin repeat and SOCS box protein 16, ASB-16, ASB16|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of theankyrin repeat and SOCS box-containing (ASB) family of proteins.They contain ankyrin repeat sequence and a SOCS box domain. TheSOCS box serves to couple suppressor of cytokine signalling (SOCS)proteins and their binding partners with the elongin B and Ccomplex, possibly targeting them for degradation. [provided byRefSeq].
Rose, J. Phd, et al. Mol. Med. (2010) In press :Wu, C., et al. Proteomics 7(11):1775-1785(2007)Kohroki, J., et al. FEBS Lett. 579(30):6796-6802(2005)Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002)
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