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C15orf38 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7Z6K5
Clone Names 91218282
Peptide ID 91218282
Additional Information
Gene ID 348110
Other Names Arpin, Arp2/3 inhibition protein, ARPIN, C15orf38
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARPIN
Synonyms C15orf38
Function Regulates actin polymerization by inhibiting the actin- nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence.
Cellular Location Cell projection, lamellipodium. Note=Colocalized with the WAVE complex at lamelliupodium tip.
Research Areas
Citations (0)

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References

Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010) :Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 80.00
Cat# BP10842a
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