|Other Names||BCL-6 corepressor-like protein 1, BCoR-L1, BCoR-like protein 1, BCORL1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence- specific DNA-binding proteins such as BCL6. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor.|
|Tissue Location||Detected in testis and prostate. Detected at lower levels in peripheral blood leukocytes and spleen|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a transcriptionalcorepressor that is found tethered to promoter regions byDNA-binding proteins. The encoded protein can interact with severaldifferent class II histone deacetylases to repress transcription.Two transcript variants encoding different isoforms have been foundfor this gene.
Pagan, J.K., et al. J. Biol. Chem. 282(20):15248-15257(2007)Lose, F., et al. Breast Cancer Res. 9 (4), R54 (2007) :
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