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BCORL1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q5H9F3
Clone Names 91230009
Additional Information
Gene ID 63035
Other Names BCL-6 corepressor-like protein 1, BCoR-L1, BCoR-like protein 1, BCORL1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCORL1 (HGNC:25657)
Function Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA- binding proteins such as BCL6. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor.
Cellular Location Nucleus.
Tissue Location Detected in testis and prostate. Detected at lower levels in peripheral blood leukocytes and spleen
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a transcriptionalcorepressor that is found tethered to promoter regions byDNA-binding proteins. The encoded protein can interact with severaldifferent class II histone deacetylases to repress transcription.Two transcript variants encoding different isoforms have been foundfor this gene.

References

Pagan, J.K., et al. J. Biol. Chem. 282(20):15248-15257(2007)Lose, F., et al. Breast Cancer Res. 9 (4), R54 (2007) :

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$ 277.78
Cat# BP10847a
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