|Other Names||Protein DENND6A, DENN domain-containing protein 6A, DENND6A, FAM116A|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes.|
|Cellular Location||Recycling endosome. Cytoplasm|
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Belongs to the FAM116 family.
Kimura, K., et al. Genome Res. 16(1):55-65(2006)Ota, T., et al. Nat. Genet. 36(1):40-45(2004)
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