C11orf79 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NX18 |
---|---|
Clone Names | 100120102 |
Gene ID | 54949 |
---|---|
Other Names | Succinate dehydrogenase assembly factor 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03057}, SDH assembly factor 2 {ECO:0000255|HAMAP-Rule:MF_03057}, SDHAF2 {ECO:0000255|HAMAP-Rule:MF_03057}, SDHAF2 {ECO:0000255|HAMAP-Rule:MF_03057} |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SDHAF2 {ECO:0000255|HAMAP-Rule:MF_03057} |
---|---|
Function | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. |
Cellular Location | Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03057, ECO:0000269|PubMed:19628817} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a mitochondrial protein needed for theflavination of a succinate dehydrogenase complex subunit requiredfor activity of the complex. Mutations in this gene are associatedwith paraganglioma.
References
Bayley, J.P., et al. Lancet Oncol. 11(4):366-372(2010)Gaal, J., et al. J. Clin. Endocrinol. Metab. 95(3):1274-1278(2010)Hao, H.X., et al. Science 325(5944):1139-1142(2009)Stelzl, U., et al. Cell 122(6):957-968(2005)Baysal, B.E., et al. Am. J. Hum. Genet. 60(1):121-132(1997)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.