|Other Names||Vacuolar protein sorting-associated protein 52 homolog, SAC2 suppressor of actin mutations 2-like protein, VPS52, SACM2L|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.|
|Cellular Location||Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that is similar to the yeastsuppressor of actin mutations 2 gene. The yeast protein forms asubunit of the tetrameric Golgi-associated retrograde proteincomplex that is involved in vesicle trafficking from from bothearly and late endosomes, back to the trans-Golgi network. Thisgene is located on chromosome 6 in a head-to-head orientation withthe gene encoding ribosomal protein S18.
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :Perez-Victoria, F.J., et al. Mol. Cell. Biol. 29(19):5251-5263(2009)Perez-Victoria, F.J., et al. Mol. Biol. Cell 19(6):2350-2362(2008)Liewen, H., et al. Exp. Cell Res. 306(1):24-34(2005)Mungall, A.J., et al. Nature 425(6960):805-811(2003)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.