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CASP5 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P51878
Clone Names 80410105
Peptide ID 80410105
Additional Information
Gene ID 838
Other Names Caspase-5, CASP-5, ICE(rel)-III, Protease ICH-3, Protease TY, Caspase-5 subunit p20, Caspase-5 subunit p10, CASP5, ICH3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CASP5
Synonyms ICH3
Function Mediator of programmed cell death (apoptosis).
Tissue Location Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle
Research Areas
Citations (0)

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This gene encodes a member of the cysteine-aspartic acidprotease (caspase) family. Sequential activation of caspases playsa central role in the execution-phase of cell apoptosis. Caspasesexist as inactive proenzymes which undergo proteolytic processingat conserved aspartic residues to produce two subunits, large andsmall, that dimerize to form the active enzyme. Overexpression ofthe active form of this enzyme induces apoptosis in fibroblasts.Max, a central component of the Myc/Max/Mad transcriptionregulation network important for cell growth, differentiation, andapoptosis, is cleaved by this protein; this process requiresFas-mediated dephosphorylation of Max. The expression of this geneis regulated by interferon-gamma and lipopolysaccharide.Alternatively spliced transcript variants have been identified forthis gene.


Ulybina, Y.M., et al. Exp. Gerontol. 45(9):726-729(2010)Notaridou, M., et al. Int. J. Cancer (2010) In press :Kim, M.S., et al. APMIS 118(4):308-312(2010)Liang, X.S., et al. Br. J. Haematol. 146(4):418-423(2009)Eckhart, L., et al. Biochem. Biophys. Res. Commun. 348(2):682-688(2006)

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$ 80.00
Cat# BP10944b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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