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CEBPG Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P53567
Clone Names 80924127
Peptide ID 80924127
Additional Information
Gene ID 1054
Other Names CCAAT/enhancer-binding protein gamma, C/EBP gamma, CEBPG
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CEBPG
Function Transcription factor that binds to the promoter and the enhancer regions of target genes. Binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene (PubMed:7665092). Binds to the promoter and the enhancer of the immunoglobulin heavy chain. Binds to GPE1, a cis-acting element in the G-CSF gene promoter.
Cellular Location Nucleus {ECO:0000250|UniProtKB:P53568}.
Research Areas
Citations (0)

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Background

The C/EBP family of transcription factors regulates viraland cellular CCAAT/enhancer element-mediated transcription. C/EBPproteins contain the bZIP region, which is characterized by twomotifs in the C-terminal half of the protein: a basic regioninvolved in DNA binding and a leucine zipper motif involved indimerization. The C/EBP family consist of several related proteins,C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that formhomodimers and that form heterodimers with each other.CCAAT/enhancer binding protein gamma may cooperate with Fos to bindPRE-I enhancer elements.

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)Crawford, E.L., et al. Carcinogenesis 28(12):2552-2559(2007)Mullins, D.N., et al. BMC Cancer 5, 141 (2005) :Newman, J.R., et al. Science 300(5628):2097-2101(2003)Hattori, T., et al. Oncogene 22(9):1273-1280(2003)

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$ 80.00
Cat# BP10951b
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