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CEBPG Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P53567 |
|---|---|
| Clone Names | 80924127 |
| Gene ID | 1054 |
|---|---|
| Other Names | CCAAT/enhancer-binding protein gamma, C/EBP gamma, CEBPG |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CEBPG |
|---|---|
| Function | Transcription factor that binds to the promoter and the enhancer regions of target genes. Binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene (PubMed:7665092). Binds to the promoter and the enhancer of the immunoglobulin heavy chain. Binds to GPE1, a cis-acting element in the G-CSF gene promoter. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:P53568}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The C/EBP family of transcription factors regulates viraland cellular CCAAT/enhancer element-mediated transcription. C/EBPproteins contain the bZIP region, which is characterized by twomotifs in the C-terminal half of the protein: a basic regioninvolved in DNA binding and a leucine zipper motif involved indimerization. The C/EBP family consist of several related proteins,C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that formhomodimers and that form heterodimers with each other.CCAAT/enhancer binding protein gamma may cooperate with Fos to bindPRE-I enhancer elements.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Crawford, E.L., et al. Carcinogenesis 28(12):2552-2559(2007)Mullins, D.N., et al. BMC Cancer 5, 141 (2005) :Newman, J.R., et al. Science 300(5628):2097-2101(2003)Hattori, T., et al. Oncogene 22(9):1273-1280(2003)
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