|Other Names||CCAAT/enhancer-binding protein gamma, C/EBP gamma, CEBPG|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites.|
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Provided below are standard protocols that you may find useful for product applications.
The C/EBP family of transcription factors regulates viraland cellular CCAAT/enhancer element-mediated transcription. C/EBPproteins contain the bZIP region, which is characterized by twomotifs in the C-terminal half of the protein: a basic regioninvolved in DNA binding and a leucine zipper motif involved indimerization. The C/EBP family consist of several related proteins,C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that formhomodimers and that form heterodimers with each other.CCAAT/enhancer binding protein gamma may cooperate with Fos to bindPRE-I enhancer elements.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Crawford, E.L., et al. Carcinogenesis 28(12):2552-2559(2007)Mullins, D.N., et al. BMC Cancer 5, 141 (2005) :Newman, J.R., et al. Science 300(5628):2097-2101(2003)Hattori, T., et al. Oncogene 22(9):1273-1280(2003)
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