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WIPF2 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8TF74
Clone Names 91102326
Additional Information
Gene ID 147179
Other Names WAS/WASL-interacting protein family member 2, WASP-interacting protein-related protein, WIP- and CR16-homologous protein, WIP-related protein, WIPF2, WICH, WIRE
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name WIPF2
Synonyms WICH, WIRE
Function Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system.
Cellular Location Cytoplasm, cytoskeleton Note=Localized to stress fibers and bundles of actin filaments
Tissue Location Expressed mainly in brain, colon, lung and stomach (at protein level). Ubiquitously expressed, with high expression in brain, kidney, lung, and placenta.
Research Areas
Citations (0)
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Background

This gene encodes a WASP interacting protein (WIP)-relatedprotein. It has been shown that this protein has a role in theWASP-mediated organization of the actin cytoskeleton and that thisprotein is a potential link between the activated platelet-derivedgrowth factor receptor and the actin polymerization machinery.

References

Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)Salazar, M.A., et al. J. Biol. Chem. 278(49):49031-49043(2003)Aspenstrom, P. Exp. Cell Res. 279(1):21-33(2002)Kato, M., et al. Biochem. Biophys. Res. Commun. 291(1):41-47(2002)

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$ 277.78
Cat# BP10977b
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