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TDRD7 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8NHU6
Clone Names 91113182
Peptide ID 91113182
Additional Information
Gene ID 23424
Other Names Tudor domain-containing protein 7, PCTAIRE2-binding protein, Tudor repeat associator with PCTAIRE-2, Trap, TDRD7, PCTAIRE2BP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TDRD7
Function Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.
Cellular Location Cytoplasm. Note=Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity).
Research Areas
Citations (0)

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TDRD7, also known as Tudor domain containing protein 7, is a component of chromatoid bodies in spermatids (named processing bodies or P-bodies in somatic cells). It is found in a mRNP complex together with TDRD1, TDRD6 and DDX4. It is also found in a complex with CABLES1, PCTK2 and PIWIL1. TDRD7 has been shown to interact with histone H3 tri-methylated at K9 in vitro.


Lim, J., et al. Cell 125(4):801-814(2006)Conte, N., et al. Oncogene 22(50):8102-8116(2003)Lauffart, B., et al. Biochem. J. 363 (PT 1), 195-200 (2002) :Yamochi, T., et al. Biochem. Biophys. Res. Commun. 286(5):1045-1050(2001)Hirose, T., et al. Eur. J. Biochem. 267(7):2113-2121(2000)

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$ 80.00
Cat# BP10982b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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