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BCLAF1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NYF8 |
|---|---|
| Clone Names | 90121172 |
| Gene ID | 9774 |
|---|---|
| Other Names | Bcl-2-associated transcription factor 1, Btf, BCLAF1, BTF, KIAA0164 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | BCLAF1 |
|---|---|
| Synonyms | BTF, KIAA0164 |
| Function | Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. |
| Cellular Location | Cytoplasm. Nucleus. Nucleus speckle. Nucleus, nucleoplasm |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a transcriptional repressor thatinteracts with several members of the BCL2 family of proteins.Overexpression of this protein induces apoptosis, which can besuppressed by co-expression of BCL2 proteins. The protein localizesto dot-like structures throughout the nucleus, and redistributes toa zone near the nuclear envelope in cells undergoing apoptosis.Multiple transcript variants encoding different isoforms have beenfound for this gene.
References
Sarras, H., et al. ScientificWorldJournal 10, 1450-1461 (2010) :Renert, A.F., et al. J. Proteome Res. 8(10):4810-4822(2009)Liu, H., et al. Mol. Cell. Biol. 27(24):8480-8491(2007)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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