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BCLAF1 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NYF8
Clone Names 90121172
Peptide ID 90121172
Additional Information
Gene ID 9774
Other Names Bcl-2-associated transcription factor 1, Btf, BCLAF1, BTF, KIAA0164
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCLAF1
Synonyms BTF, KIAA0164
Function Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Cellular Location Cytoplasm. Nucleus. Nucleus speckle. Nucleus, nucleoplasm
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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Background

This gene encodes a transcriptional repressor thatinteracts with several members of the BCL2 family of proteins.Overexpression of this protein induces apoptosis, which can besuppressed by co-expression of BCL2 proteins. The protein localizesto dot-like structures throughout the nucleus, and redistributes toa zone near the nuclear envelope in cells undergoing apoptosis.Multiple transcript variants encoding different isoforms have beenfound for this gene.

References

Sarras, H., et al. ScientificWorldJournal 10, 1450-1461 (2010) :Renert, A.F., et al. J. Proteome Res. 8(10):4810-4822(2009)Liu, H., et al. Mol. Cell. Biol. 27(24):8480-8491(2007)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 80.00
Cat# BP10988b
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