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UPP2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O95045 |
|---|---|
| Clone Names | 91119323 |
| Gene ID | 151531 |
|---|---|
| Other Names | Uridine phosphorylase 2, UPase 2, UrdPase 2, UPP2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | UPP2 (HGNC:23061) |
|---|---|
| Function | Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (PubMed:12849978, PubMed:21855639). Shows broad substrate specificity and can also accept deoxyuridine and other analogous compounds (PubMed:12849978). |
| Tissue Location | Predominantly expressed in kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
References
Maestrini, E., et al. Mol. Psychiatry 15(9):954-968(2010)Lamesch, P., et al. Genomics 89(3):307-315(2007)Johansson, M. Biochem. Biophys. Res. Commun. 307(1):41-46(2003)Russell, R.L., et al. J. Biol. Chem. 276(16):13302-13307(2001)
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