C20orf7 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q5TEU4 |
---|---|
Clone Names | 100107291 |
Gene ID | 79133 |
---|---|
Other Names | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5, Probable methyltransferase C20orf7, mitochondrial, 211-, NDUFAF5, C20orf7 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NDUFAF5 (HGNC:15899) |
---|---|
Function | Arginine hydroxylase involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT- ND1) at early stages (PubMed:18940309, PubMed:27226634). Acts by mediating hydroxylation of 'Arg-111' of NDUFS7 (PubMed:27226634). May also have methyltransferase activity (Probable). |
Cellular Location | Mitochondrion inner membrane. Note=Peripherally localized on the matrix face of the mitochondrial inner membrane |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The NADH-ubiquinone oxidoreductase complex (complex I) ofthe mitochondrial respiratory chain catalyzes the transfer ofelectrons from NADH to ubiquinone, and consists of at least 43subunits. The complex is located in the inner mitochondrialmembrane. This gene encodes a mitochondrial protein that isassociated with the matrix face of the mitochondrial inner membraneand is required for complex I assembly. A mutation in this generesults in mitochondrial complex I deficiency. Multiple transcriptvariants encoding different isoforms have been found for this gene.
References
Gerards, M., et al. J. Med. Genet. 47(8):507-512(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Sugiana, C., et al. Am. J. Hum. Genet. 83(4):468-478(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.