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GNL3L Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9NVN8
Clone Names 91208265
Peptide ID 91208265
Additional Information
Gene ID 54552
Other Names Guanine nucleotide-binding protein-like 3-like protein, GNL3L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GNL3L
Function Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Cellular Location Nucleus, nucleolus
Research Areas
Citations (0)

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The protein encoded by this gene appears to be a nucleolarGTPase that is essential for ribosomal pre-rRNA processing and cellproliferation. Two transcript variants encoding the same proteinhave been found for this gene.


Rao, M.R., et al. J. Mol. Biol. 364(4):637-654(2006)Du, X., et al. Mol. Biol. Cell 17(1):460-474(2006)

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$ 80.00
Cat# BP11045a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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