SULT1C3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6IMI6 |
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Clone Names | 100120251 |
Gene ID | 442038 |
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Other Names | Sulfotransferase 1C3, ST1C3, SULT1C3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SULT1C3 |
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Function | [Isoform 1]: Sulfotransferase that utilizes 3'-phospho-5'- adenylyl sulfate (PAPS) as sulfonate donor. Has sulfotransferase activity towards various substrates, such as bile acids, thyroid hormones and toward xenobiotic compounds such as chloro phenols and hydroxypyrenes. Lithocholic acid appears to be the best substrate among the endogenous compounds tested and 3,3',5,5'-tetrachloro-4,4'- biphenyldiol shows the highest specific activity among the xenobiotic compounds. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q80VR3}. |
Tissue Location | [Isoform 1]: Not detectable in any of the tissues tested. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Has low sulphotransferase activity towards various substrates with alcohol groups (in vitro). May catalyze the sulfate conjugation of xenobiotic compounds and endogenous substrates.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Meinl, W., et al. Food Chem. Toxicol. 46(4):1249-1256(2008)Allali-Hassani, A., et al. PLoS Biol. 5 (5), E97 (2007) :Hillier, L.W., et al. Nature 434(7034):724-731(2005)Freimuth, R.R., et al. Pharmacogenomics J. 4(1):54-65(2004)
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