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CLEC11A Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y240 |
|---|---|
| Clone Names | 70319167 |
| Gene ID | 6320 |
|---|---|
| Other Names | C-type lectin domain family 11 member A, C-type lectin superfamily member 3, Lymphocyte secreted C-type lectin, Stem cell growth factor, p47, CLEC11A, CLECSF3, LSLCL, SCGF |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CLEC11A |
|---|---|
| Synonyms | CLECSF3, LSLCL, SCGF |
| Function | Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts (PubMed:27976999). Important for repair and maintenance of adult bone (By similarity). |
| Cellular Location | Cytoplasm. Secreted |
| Tissue Location | Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the C-type lectinsuperfamily. The encoded protein is a secreted sulfatedglycoprotein and functions as a growth factor for primitivehematopoietic progenitor cells. An alternative splice variant hasbeen described but its biological nature has not been determined.
References
Ouma, C., et al. Infect. Immun. 78(1):453-460(2010)Keller, C.C., et al. Infect. Immun. 77(9):3864-3871(2009)Lan, C.C., et al. Br. J. Dermatol. 160(6):1180-1187(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Hollenbeck, S.T., et al. J. Surg. Res. 120(2):288-294(2004)
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