|Other Names||Arginine--tRNA ligase, cytoplasmic, Arginyl-tRNA synthetase, ArgRS, RARS|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis (PubMed:25288775). Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1 (PubMed:17443684).|
|Cellular Location||Cytoplasm. Cytoplasm, cytosol|
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Provided below are standard protocols that you may find useful for product applications.
Aminoacyl-tRNA synthetases catalyze the aminoacylation oftRNA by their cognate amino acid. Because of their central role inlinking amino acids with nucleotide triplets contained in tRNAs,aminoacyl-tRNA synthetases are thought to be among the firstproteins that appeared in evolution. Arginyl-tRNA synthetasebelongs to the class-I aminoacyl-tRNA synthetase family. [providedby RefSeq].
Bottoni, A., et al. J. Cell. Physiol. 212(2):293-297(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Ling, C., et al. J. Biol. Chem. 280(41):34755-34763(2005)Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)Kaminska, M., et al. Biochemistry 40(47):14309-14316(2001)
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