|Other Names||Arginine--tRNA ligase, cytoplasmic, Arginyl-tRNA synthetase, ArgRS, RARS|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.|
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Provided below are standard protocols that you may find useful for product applications.
Aminoacyl-tRNA synthetases catalyze the aminoacylation oftRNA by their cognate amino acid. Because of their central role inlinking amino acids with nucleotide triplets contained in tRNAs,aminoacyl-tRNA synthetases are thought to be among the firstproteins that appeared in evolution. Arginyl-tRNA synthetasebelongs to the class-I aminoacyl-tRNA synthetase family. [providedby RefSeq].
Bottoni, A., et al. J. Cell. Physiol. 212(2):293-297(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Ling, C., et al. J. Biol. Chem. 280(41):34755-34763(2005)Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)Kaminska, M., et al. Biochemistry 40(47):14309-14316(2001)
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