AASS Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UDR5 |
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Clone Names | 80109102 |
Gene ID | 10157 |
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Other Names | Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | AASS (HGNC:17366) |
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Function | Bifunctional enzyme that catalyzes the first two steps in lysine degradation. |
Cellular Location | Mitochondrion. |
Tissue Location | Expressed in all 16 tissues examined with highest expression in the liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a bifunctional enzyme that catalyzes thefirst two steps in the mammalian lysine degradation pathway. TheN-terminal and the C-terminal portions of this enzyme containlysine-ketoglutarate reductase and saccharopine dehydrogenaseactivity, respectively, resulting in the conversion of lysine toalpha-aminoadipic semialdehyde. Mutations in this gene areassociated with familial hyperlysinemia.
References
Sacksteder, K.A., et al. Am. J. Hum. Genet. 66(6):1736-1743(2000)Papes, F., et al. Biochem. J. 344 PT 2, 555-563 (1999) :
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