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AASS Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UDR5
Clone Names 80109102
Peptide ID 80109102
Additional Information
Gene ID 10157
Other Names Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AASS
Function Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively.
Cellular Location Mitochondrion.
Tissue Location Expressed in all 16 tissues examined with highest expression in the liver
Research Areas
Citations (0)

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Background

This gene encodes a bifunctional enzyme that catalyzes thefirst two steps in the mammalian lysine degradation pathway. TheN-terminal and the C-terminal portions of this enzyme containlysine-ketoglutarate reductase and saccharopine dehydrogenaseactivity, respectively, resulting in the conversion of lysine toalpha-aminoadipic semialdehyde. Mutations in this gene areassociated with familial hyperlysinemia.

References

Sacksteder, K.A., et al. Am. J. Hum. Genet. 66(6):1736-1743(2000)Papes, F., et al. Biochem. J. 344 PT 2, 555-563 (1999) :

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$ 80.00
Cat# BP11094b
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