|Other Names||Acetyl-CoA acetyltransferase, mitochondrial, Acetoacetyl-CoA thiolase, T2, ACAT1, ACAT, MAT|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a major role in ketone body metabolism.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a mitochondrially localized enzyme thatcatalyzes the reversible formation of acetoacetyl-CoA from twomolecules of acetyl-CoA. Defects in this gene are associated with3-ketothiolase deficiency, an inborn error of isoleucine catabolismcharacterized by urinary excretion of 2-methyl-3-hydroxybutyricacid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)Sakashita, N., et al. J. Lipid Res. 51(6):1263-1272(2010)Reynolds, C.A., et al. Hum. Mol. Genet. 19(10):2068-2078(2010)Fukao, T., et al. Mol. Genet. Metab. 100(1):37-41(2010)Thummler, S., et al. Tohoku J. Exp. Med. 220(1):27-31(2010)
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