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DFNB31 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9P202
Clone Names 80722041
Peptide ID 80722041
Additional Information
Gene ID 25861
Other Names Whirlin, Autosomal recessive deafness type 31 protein, DFNB31, KIAA1526, WHRN
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DFNB31
Synonyms KIAA1526, WHRN
Function Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear.
Cellular Location Cytoplasm. Cell projection, stereocilium. Cell projection, growth cone. Note=Detected at the level of stereocilia in inner outer hair cells of the cochlea and vestibule. Colocalizes with the growing ends of actin filaments (By similarity). Colocalizes with MPP1 in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). {ECO:0000250, ECO:0000269|PubMed:17584769}
Research Areas
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This gene is thought to function in the organization andstabilization of sterocilia elongation and actin cystoskeletalassembly, based on studies of the related mouse gene. Mutations inthis gene have been associated with autosomal recessivenon-syndromic deafness and Usher Syndrome. Alternative splicing ofthis gene results in multiple transcript variants encodingdifferent isoforms.


Letra, A., et al. Am. J. Med. Genet. A 152A (7), 1701-1710 (2010) :Secolin, R., et al. Psychiatr. Genet. 20(3):126-129(2010)Aller, E., et al. Mol. Vis. 16, 495-500 (2010) :Toiyama, Y., et al. Int. J. Oncol. 35(4):709-715(2009)Gosens, I., et al. Hum. Mol. Genet. 16(16):1993-2003(2007)

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$ 80.00
Cat# BP11113c
(40 western blots)
Availability: In Stock
Bulk Size
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