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TDRD1 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9BXT4
Clone Names 91230104
Peptide ID 91230104
Additional Information
Gene ID 56165
Other Names Tudor domain-containing protein 1, Cancer/testis antigen 411, CT411, TDRD1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TDRD1
Function Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins (By similarity).
Cellular Location Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis Also present in chromatoid body (By similarity).
Tissue Location Testis and ovary specific. Also expressed in several cancers.
Research Areas
Citations (0)

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This gene is similar to a mouse gene that encodes a tudordomain protein. Alternatively spliced transcript variants have beendescribed but their full length sequences have not been determined.


Wu, C., et al. Proteomics 7(11):1775-1785(2007)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Wang, P.J., et al. Nat. Genet. 27(4):422-426(2001)

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$ 80.00
Cat# BP11148b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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