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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   HMOF/MYST1 Antibody (C-term) Blocking Peptide   

HMOF/MYST1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9H7Z6
Clone Names 71130164
Peptide ID 71130164
Additional Information
Gene ID 84148
Other Names Histone acetyltransferase KAT8, Lysine acetyltransferase 8, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, hMOF, KAT8, MOF, MYST1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1114b was selected from the C-term region of human HMOF/MYST1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KAT8
Synonyms MOF, MYST1
Function Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'.
Cellular Location Nucleus. Chromosome
Research Areas
Citations (0)

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The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3; MIM 601408), yeast YBF2 and SAS2, and TIP60 (HTATIP; MIM 601409). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin (Neal et al., 2000 [PubMed 10786633]).[supplied by OMIM].


Rea,S.,Oncogene 26 (37), 5385-5394 (2007)Pfister,S.,Int. J. Cancer 122 (6), 1207-1213 (2008)Gupta,A.,Mol. Cell. Biol. 28 (1), 397-409 (2008)

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$ 80.00
Cat# BP1114b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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