|Other Names||Complement C1q-like protein 3, C1q and tumor necrosis factor-related protein 13, C1q/TNF-related protein 13, C1QL3, CTRP13|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production (By similarity).|
|Tissue Location||Highly expressed in adipose tissue, with expression levels at least 2 orders of magnitude higher than in other tissues, including brain and kidney|
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May have S-adenosyl-L-methionine-dependent methyl-transferase activity (Potential).
Deloukas, P., et al. Nature 429(6990):375-381(2004)Koide, T., et al. J. Biol. Chem. 275(36):27957-27963(2000)
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