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Synthetic peptide
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| Primary Accession | Q96CB9 |
|---|---|
| Clone Names | 91218007 |
| Peptide ID | 91218007 |
| Gene ID | 387338 |
|---|---|
| Other Names | 5-methylcytosine rRNA methyltransferase NSUN4, 211-, NOL1/NOP2/Sun domain family member 4, NSUN4 |
| Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NSUN4 |
|---|---|
| Function | Involved in mitochondrial ribosome assembly. 5- methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4. |
| Cellular Location | Mitochondrion |
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Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the methyltransferase superfamily. May have S-adenosyl-L-methionine-dependent methyl-transferase activity.
References
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :
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