|Other Names||OTU domain-containing protein 1, DUBA-7, OTUD1, DUBA7, OTDC1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Deubiquitinating enzyme that specifically hydrolyzes 'Lys-63'-linked polyubiquitin to monoubiquitin.|
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Provided below are standard protocols that you may find useful for product applications.
Deubiquitinating enzymes (DUBs; see MIM 603478) areproteases that specifically cleave ubiquitin (MIM 191339) linkages,negating the action of ubiquitin ligases. DUBA7 belongs to a DUBsubfamily characterized by an ovarian tumor (OTU) domain.[suppliedby OMIM].
Franke, A., et al. Gastroenterology 135(4):1207-1215(2008)Kayagaki, N., et al. Science 318(5856):1628-1632(2007)Deloukas, P., et al. Nature 429(6990):375-381(2004)Makarova, K.S., et al. Trends Biochem. Sci. 25(2):50-52(2000)
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