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THEMIS Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8N1K5
Clone Names 100126082
Peptide ID 100126082
Additional Information
Gene ID 387357
Other Names Protein THEMIS, Thymocyte-expressed molecule involved in selection, THEMIS, C6orf190, C6orf207
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C6orf190, C6orf207
Function Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity).
Cellular Location Cytoplasm. Nucleus
Research Areas
Citations (0)

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This gene encodes a protein that plays a regulatory rolein both positive and negative T-cell selection during latethymocyte development. The protein functions through T-cell antigenreceptor signaling, and is necessary for proper lineage commitmentand maturation of T-cells. Alternative splicing results in multipletranscript variants.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)Bhatti, P., et al. Radiat. Res. 173(2):214-224(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Patrick, M.S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(38):16345-16350(2009)

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$ 80.00
Cat# BP11184b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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