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MTSS1L Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q765P7 |
|---|---|
| Clone Names | 100126128 |
| Gene ID | 92154 |
|---|---|
| Other Names | MTSS1-like protein, Actin-bundling with BAIAP2 homology protein 1, ABBA-1, MTSS1L |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MTSS2 (HGNC:25094) |
|---|---|
| Function | Involved in plasma membrane dynamics. Potentiated PDGF- mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation (PubMed:14752106). May function in actin bundling (PubMed:14752106). |
| Cellular Location | Cytoplasm. Cell projection, ruffle. Note=Colocalizes with RAC1 within membrane ruffles. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. Forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. Also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3 (By similarity).
References
Zheng, D., et al. Biochem. Biophys. Res. Commun. 401(4):527-532(2010)Yamagishi, A., et al. J. Biol. Chem. 279(15):14929-14936(2004)
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