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AHCY Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P23526 |
|---|---|
| Clone Names | 80102113 |
| Gene ID | 191 |
|---|---|
| Other Names | Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, AHCY, SAHH |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AHCY |
|---|---|
| Synonyms | SAHH |
| Function | Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (PubMed:10933798). Binds copper ions (By similarity). |
| Cellular Location | Cytoplasm. Melanosome. Nucleus. Endoplasmic reticulum. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
S-adenosylhomocysteine hydrolase belongs to theadenosylhomocysteinase family. It catalyzes the reversiblehydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado)and L-homocysteine (Hcy). Thus, it regulates the intracellularS-adenosylhomocysteine (SAH) concentration thought to be importantfor transmethylation reactions. Deficiency in this protein is oneof the different causes of hypermethioninemia. Alternativelyspliced transcript variants encoding different isoforms have beenfound for this gene.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Gass, N., et al. J Affect Disord 126 (1-2), 134-139 (2010) :Giusti, B., et al. Thromb. Haemost. 104(2):231-242(2010)Levine, A.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1812-1821(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
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