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PRRT1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q99946 |
|---|---|
| Other Accession | NP_085154.3 |
| Clone Names | 90713169 |
| Gene ID | 80863 |
|---|---|
| Other Names | Proline-rich transmembrane protein 1, Dispanin subfamily D member 1, DSPD1, PRRT1, C6orf31, NG5 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PRRT1 (HGNC:13943) |
|---|---|
| Function | Required to maintain a pool of extrasynaptic AMPA-regulated glutamate receptors (AMPAR) which is necessary for synapse development and function. Regulates basal AMPAR function and synaptic transmission during development but is dispensable at mature hippocampal synapses. Plays a role in regulating basal phosphorylation levels of glutamate receptor GRIA1 and promotes GRIA1 and GRIA2 cell surface expression. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q6MG82}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q6MG82} Synapse {ECO:0000250|UniProtKB:Q6MG82} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :McKinnon, E., et al. Diabetes Obes Metab 11 SUPPL 1, 92-100 (2009) :Vignal, C., et al. Arthritis Rheum. 60(1):53-62(2009)Xie, T., et al. Genome Res. 13(12):2621-2636(2003)
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