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CRH Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P06850
Clone Names 90429086
Peptide ID 90429086
Additional Information
Gene ID 1392
Other Names Corticoliberin, Corticotropin-releasing factor, CRF, Corticotropin-releasing hormone, CRH
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRH
Function This hormone from hypothalamus regulates the release of corticotropin from pituitary gland.
Cellular Location Secreted.
Research Areas
Citations (0)

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Corticotropin-releasing hormone is secreted by theparaventricular nucleus (PVN) of the hypothalamus in response tostress. Marked reduction in this protein has been observed inassociation with Alzheimer disease and autosomal recessivehypothalamic corticotropin deficiency has multiple and potentiallyfatal metabolic consequences including hypoglycemia and hepatitis.In addition to production in the hypothalamus, this protein is alsosynthesized in peripheral tissues, such as T lymphocytes and ishighly expressed in the placenta. In the placenta it is a markerthat determines the length of gestation and the timing ofparturition and delivery. A rapid increase in circulating levels ofthe hormone occurs at the onset of parturition, suggesting that, inaddition to its metabolic functions, this protein may act as atrigger for parturition.


Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :Holliday, K.L., et al. J Psychosom Res 68(5):469-474(2010)Binder, E.B., et al. Arch. Gen. Psychiatry 67(4):369-379(2010)Kageyama, K., et al. Vitam. Horm. 82, 301-317 (2010) :

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$ 80.00
Cat# BP11244b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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