|Other Names||Keratin, type II cytoskeletal 73, Cytokeratin-73, CK-73, Keratin-73, K73, Type II inner root sheath-specific keratin-K6irs3, Type-II keratin Kb36, KRT73, K6IRS3, KB36, KRT6IRS3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||K6IRS3, KB36, KRT6IRS3|
|Function||Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable).|
|Tissue Location||Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, it is expressed between the lowermost bulb region of the cuticle and the region where Henle cells undergo abrupt terminal differentiation Detected up to the uppermost cortex region where cuticle cells terminally differentiate (at protein level)|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Keratins are intermediate filament proteins responsiblefor the structural integrity of epithelial cells and are subdividedinto epithelial keratins and hair keratins. This gene encodes aprotein that is expressed in the inner root sheath of hairfollicles. The type II keratins are clustered in a region ofchromosome 12q13.
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)Langbein, L., et al. J. Invest. Dermatol. 120(4):512-522(2003)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.