|Other Names||Phosphatidylinositol 4-phosphate 5-kinase-like protein 1, PI(4)P 5-kinase-like protein 1, PtdIns(4)P-5-kinase-like protein 1, PIP5KL1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3.|
|Cellular Location||Cytoplasm. Membrane. Note=Localized to large cytoplasmic vesicular structures.|
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Provided below are standard protocols that you may find useful for product applications.
PIP5KL1 is a phosphoinositide kinase-like protein thatlacks intrinsic lipid kinase activity but associates with type IPIPKs (see PIP5K1A; MIM 603275) and may play a role in localizationof PIPK activity (Chang et al., 2004 [PubMed 14701839]).[suppliedby OMIM].
Shi, L., et al. Mol. Biol. Rep. 37(5):2189-2198(2010)Lamesch, P., et al. Genomics 89(3):307-315(2007)Chang, J.D., et al. J. Biol. Chem. 279(12):11672-11679(2004)
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