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RAB12 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6IQ22
Other Accession NP_001020471.2
Clone Names 100126071
Additional Information
Gene ID 201475
Other Names Ras-related protein Rab-12, RAB12
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB12
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity).
Cellular Location Recycling endosome membrane {ECO:0000250|UniProtKB:P35283}; Lipid-anchor; Cytoplasmic side. Lysosome membrane {ECO:0000250|UniProtKB:P35283}; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane {ECO:0000250|UniProtKB:P51152}. Cytoplasmic vesicle, autophagosome {ECO:0000250|UniProtKB:P35283}
Research Areas
Citations (0)
citation

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References

Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :

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$ 277.78
Cat# BP11360a
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