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TMEM201 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q5SNT2
Clone Names 100126174
Peptide ID 100126174
Additional Information
Gene ID 199953
Other Names Transmembrane protein 201, Spindle-associated membrane protein 1, TMEM201, NET5, SAMP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMEM201
Synonyms NET5, SAMP1
Function Involved in nuclear movement during fibroblast polarization and migration. Proposed to be involved in actin- dependent nuclear movement via association with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow (By similarity). Overexpression can recruit Ran GTPase to the nuclear periphery (PubMed:27541860).
Cellular Location Isoform 2: Nucleus inner membrane; Multi- pass membrane protein. Cytoplasm, cytoskeleton, spindle pole. Note=The C-terminal of isoform 2 is located on the nucleoplasmic side During interphase, isoform 2 is distributed in the inner nuclear membrane in distinct micro-domains and during mitosis, it is found in the ER but it also localizes to the polar regions of the mitotic spindle.
Research Areas
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Background

Isoform SAMP1 may define a distinct membrane domain in the vicinity of the mitotic spindle.

References

Buch, C., et al. J. Cell. Sci. 122 (PT 12), 2100-2107 (2009) :

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$ 80.00
Cat# BP11369b
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