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PNLDC1 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8NA58
Other Accession NP_775787.1
Clone Names 100203005
Peptide ID 100203005
Additional Information
Gene ID 154197
Other Names Poly(A)-specific ribonuclease PARN-like domain-containing protein 1, PNLDC1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PNLDC1 (HGNC:21185)
Function 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails (PubMed:27515512). Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development (PubMed:27515512). May act as a regulator of multipotency in embryonic stem cells (By similarity).
Cellular Location Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Localizes mainly in the endoplasmic reticulum (PubMed:27515512).
Research Areas
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References

Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)Yoshida, T., et al. Int. J. Mol. Med. 24(4):539-547(2009)

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$ 80.00
Cat# BP11385b
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