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GAS2L2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8NHY3 |
|---|---|
| Clone Names | 100203253 |
| Gene ID | 246176 |
|---|---|
| Other Names | GAS2-like protein 2, GAS2-related protein on chromosome 17, Growth arrest-specific protein 2-like 2, GAS2L2, GAR17 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GAS2L2 |
|---|---|
| Synonyms | GAR17 |
| Function | Involved in the cross-linking of microtubules and microfilaments (PubMed:12584248, PubMed:24706950). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (PubMed:24706950). Enhances ADORA2- mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A (By similarity). Regulates ciliary orientation and performance in cells located in the airway (PubMed:30665704). |
| Cellular Location | Cytoplasm, cytoskeleton. Cell membrane {ECO:0000250|UniProtKB:Q5SSG4}. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cytoskeleton, cilium basal body. Note=Colocalizes with ADORA2A at neuronal processes (By similarity). Colocalizes with and tracks the tips of microtubule plus ends (PubMed:24706950) {ECO:0000250|UniProtKB:D3ZUE1, ECO:0000269|PubMed:24706950} |
| Tissue Location | Expressed in bronchial and nasal epithelial cells (at protein level) (PubMed:30665704). Expressed in brain, kidney, lung, testis, fallopian tubes, and skeletal muscle (PubMed:12584248, PubMed:30665704). Expressed at low levels in stomach and colon (PubMed:30665704). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Seems to be involved in the cross-linking of microtubules and microfilaments.
References
Goriounov, D., et al. J. Cell. Sci. 116 (PT 6), 1045-1058 (2003) :
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