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COL4A2 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P08572 |
|---|---|
| Clone Names | 80703013 |
| Gene ID | 1284 |
|---|---|
| Other Names | Collagen alpha-2(IV) chain, Canstatin, COL4A2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | COL4A2 (HGNC:2203) |
|---|---|
| Function | Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. |
| Cellular Location | Secreted, extracellular space, extracellular matrix, basement membrane |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes one of the six subunits of type IVcollagen, the major structural component of basement membranes. TheC-terminal portion of the protein, known as canstatin, is aninhibitor of angiogenesis and tumor growth. Like the other membersof the type IV collagen gene family, this gene is organized in ahead-to-head conformation with another type IV collagen gene sothat each gene pair shares a common promoter.
References
Bianchini, G., et al. J. Clin. Oncol. 28(28):4316-4323(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
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