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FAM150B Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6UX46 |
|---|---|
| Other Accession | NP_001002919.2 |
| Clone Names | 100126300 |
| Gene ID | 285016 |
|---|---|
| Other Names | Protein FAM150B, FAM150B |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ALKAL2 {ECO:0000303|PubMed:30061385, ECO:0000312|HGNC:HGNC:27683} |
|---|---|
| Function | Cytokine that acts as a physiological ligand for receptor tyrosine kinases LTK and ALK, leading to their activation (PubMed:26418745, PubMed:26630010, PubMed:30061385, PubMed:33411331, PubMed:34646012, PubMed:34819673). Cytokine-binding is sufficient to activate LTK (PubMed:34646012). In contrast, ALKAL2-driven activation of ALK is coupled with heparin-binding to ALK (PubMed:34646012). Stimulation of ALK signaling is involved in neural development and regulation of energy expenditure (PubMed:34646012, PubMed:34819673). |
| Cellular Location | Secreted. Cell membrane. Note=Following interaction with receptor tyrosine kinase ALK, associates with the cell membrane, membrane-binding is required to activate ALK |
| Tissue Location | Widely expressed with highest levels in adrenal gland and modest levels in pancreas, testis and uterus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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