LOC150763 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6NUI2 |
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Clone Names | 100203120 |
Gene ID | 150763 |
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Other Names | Glycerol-3-phosphate acyltransferase 2, mitochondrial, GPAT-2, xGPAT1, GPAT2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GPAT2 (HGNC:27168) |
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Function | Transfers an acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate producing a lysophosphatidic acid (LPA), an essential step for the triacylglycerol (TAG) and glycerophospholipids. In vitro also transfers an acyl-group from acyl-ACP to the LPA producing a phosphatidic acid (PA). Prefers arachidonoyl-CoA as the acyl donor. Required for primary processing step during piRNA biosynthesis. Molecular mechanisms by which it promotes piRNA biosynthesis are unclear and do not involve its acyltransferase activity. |
Cellular Location | Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q14DK4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q14DK4} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis (By similarity).
References
Gimeno, R.E., et al. J. Lipid Res. 49(10):2079-2088(2008)Wang, S., et al. Arch. Biochem. Biophys. 465(2):347-358(2007)
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